Someday, life with sickle cell disease
could be different.
Someday, I could be my own change,
my own donor.
Someday, life with sickle cell disease
could be different.
Someday, I could be my own change,
my own donor.
Someday, life with sickle cell disease
could be different.
Someday, I could be my own change,
my own donor.
LYFGENIA™ is the longest-studied* FDA-approved gene therapy for sickle cell disease.
About LYFGENIA
Resources & Support
FAQs
potentially decrease or stop vaso-occlusive events (VOEs)†
needed
with a history of
VOEs
production of anti-sickling
hemoglobin to potentially
decrease or stop VOEs
- The clinical trial evaluated 32 individuals for VOEs. These individuals had sickle cell disease and a history of VOEs.†
- Most evaluable individuals (88%; 28/32 individuals) did not experience any VOEs between 6-18 months after treatment‡
*The primary clinical trial that evaluated LYFGENIA started in February 2015.
†VOEs were defined as any of the following events requiring evaluation at a medical facility: an episode of acute pain with no medically determined cause other than vaso-occlusion, lasting more than 2 hours, acute chest syndrome, acute hepatic sequestration, or acute splenic sequestration.
‡Four individuals who did not experience any VOEs between 6-18 months after treatment later experienced VOEs.
Consideration Brochure
Learn about how LYFGENIA works, important safety information, the treatment process, and important discussion points to consider with your healthcare team.
Consideration Brochure
Consideration Brochure
Learn about how LYFGENIA works, important safety information, the treatment process, and important discussion points to consider with your healthcare team.
Consideration Brochure
Consideration Brochure
Learn about how LYFGENIA works, important safety information, the treatment process, and important discussion points to consider with your healthcare team.
Consideration BrochureSee important facts about LYFGENIA
LYFGENIA Medication GuideRead the full Prescribing Information
LYFGENIA Prescribing InformationRead the full Prescribing Information
LYFGENIA Prescribing InformationSee important facts about LYFGENIA
LYFGENIA Medication Guide
Curious about LYFGENIA?
When individuals living with sickle cell disease and their healthcare providers are considering LYFGENIA, bluebird bio wants to make sure they are supported. That’s why we created my bluebird support—a collection of educational resources aimed at helping individuals living with sickle cell disease and their healthcare providers stay informed in the decision-making process.
Before treatment, individuals living with sickle cell disease and their healthcare providers will work together to help consider whether LYFGENIA is right for them. A Patient Navigator can help answer additional questions about the treatment process, navigating insurance, and identifying Qualified Treatment Center options. Connect today:
Curious about LYFGENIA?
When individuals living with sickle cell disease and their healthcare providers are considering LYFGENIA, bluebird bio wants to make sure they are supported. That’s why we created my bluebird support—a collection of educational resources aimed at helping individuals living with sickle cell disease and their healthcare providers stay informed in the decision-making process.
Before treatment, individuals living with sickle cell disease and their healthcare providers will work together to help consider whether LYFGENIA is right for them. A Patient Navigator can help answer additional questions about the treatment process, navigating insurance, and identifying Qualified Treatment Center options. Connect today:
Send an email:mybluebirdsupport@bluebirdbio.com
Call: 1-844-888-NEST (6378)
Monday to Friday
Learn more about my bluebird support
Where’s LYFGENIA treatment offered?
LYFGENIA is only administered at Qualified Treatment Centers (QTCs). A QTC is a specialized hospital qualified to administer a bluebird bio gene therapy. Each LYFGENIA QTC has been carefully selected based on their expertise in areas such as transplant, cell and gene therapy, and sickle cell disease, and are trained to administer LYFGENIA.
Find a Qualified Treatment Center
Where’s LYFGENIA treatment offered?
LYFGENIA is only administered at Qualified Treatment Centers (QTCs). A QTC is a specialized hospital qualified to administer a bluebird bio gene therapy. Each LYFGENIA QTC has been carefully selected based on their expertise in areas such as transplant, cell and gene therapy, and sickle cell disease, and are trained to administer LYFGENIA.
Find a Qualified Treatment Center
Your LYFGENIA FAQs answered
LYFGENIA is a one-time gene therapy to treat sickle cell disease in individuals 12 years of age or older and a history of vaso-occlusive events.
Learn more about LYFGENIAWhen being treated with LYFGENIA your blood stem cells are collected so that LYFGENIA can be created. LYFGENIA is created by adding working copies of the HBB (beta-globin) gene to your blood stem cells. These modified cells are then returned to your body through infusion where they go through a process called engraftment, which leads to the production of new red blood cells containing functional adult hemoglobin.
Learn more about the way LYFGENIA worksIf you’re considering LYFGENIA, you should start by talking to your doctor. In addition, it may be helpful to talk to a my bluebird support Patient Navigator. Each Patient Navigator is knowledgeable about LYFGENIA and is equipped with resources to help navigate questions that you may have, including concerns about healthcare insurance or treatment planning.
Learn more about enrolling in my bluebird support to start the conversation with a Patient NavigatorThere are six key steps to being treated with LYFGENIA:
Step 1: Pre-treatment
Before receiving treatment it is important to confirm with your doctor that LYFGENIA is right for you, and whether you need to stop any medications. It's also important to understand that you will receive other medicines, including chemotherapy during the LYFGENIA treatment process. It's important to talk to your healthcare provider about the benefits and risks of all medicines involved in your treatment.
Step 2: Stem Cell Collection
Your stem cells must be collected in the hospital so that the LYFGENIA creation process can begin.
Step 3: LYFGENIA Creation
LYFGENIA is created by adding working copies of beta-globin genes to your collected cells.
Step 4: Conditioning Chemotherapy
In order to receive LYFGENIA you will need to receive conditioning with chemotherapy in the hospital to prepare your body for LYFGENIA infusion.
Step 5: LYFGENIA Infusion
Once your body and your cells are ready, LYFGENIA is administered in the hospital through an IV infusion.
Step 6: Recovery and Long-term Follow-up
You will need to stay in the hospital for approximately 3-6 weeks after receiving LYFGENIA so that doctors can monitor your health and recovery. Following treatment, you will work with your healthcare team to establish a long-term follow up plan and monitoring. Because of the risk of cancer, it is important for you to be monitored at least every 6 months for at least 15 years after LYFGENIA.
LYFGENIA is only administered at Qualified Treatment Centers (QTCs). A QTC is a specialized hospital qualified to administer a bluebird bio gene therapy.
Learn more about where to find a Qualified Treatment CenterYour out-of-pocket costs associated with gene therapy will depend on your individual coverage policies and personal circumstances. You can reach out to my bluebird support for a comprehensive overview of the anticipated costs you can expect relative to your out-of-pocket maximum for your plan and the spend to date. This includes details on out-of-pockets costs for a consult, inpatient hospital stay, and for the therapy itself. Anyone can contact my bluebird support for this information – you do not need to be prescribed LYFGENIA.
After enrolling in my bluebird support, you can connect with a Patient Navigator
Call: 1-833-888-6378
www.mybluebirdsupport.com