How does LYFGENIA™ work?
LYFGENIA is a gene addition therapy designed to add genetic material to your cells
through a viral vector.
Learn how LYFGENIA works at the genetic level—from collecting your blood stem cells to
adding new modified cells to your body.
First, cells are collected
Blood stem cells are collected from your body through mobilization and apheresis
Then, cells are modified
LYFGENIA is created by adding working copies of the HBB (beta-globin) gene to your collected cells through a viral vector
Next, LYFGENIA
is infused
Your modified cells (LYFGENIA) are returned to your body through an infusion
Functional adult
hemoglobin is produced
Your modified cells go through a process called engraftment, which leads to the production of new red blood cells containing functional adult hemoglobin
